On December 23, 2022 the FDA made their latest public announcement regarding non-hereditary DCM “FDA does not intend to release further public updates until there is meaningful new scientific information to share… While adverse event numbers can be a potential signal of an issue with an FDA regulated product, by themselves, they do not supply sufficient data to establish a causal relationship with reported product(s). FDA continues to encourage research and collaboration by academia, veterinarians, and industry.” At Pets Global, we remain committed to doing research with our diets, including measuring health parameters well above the minimum standards required by a typical AFFCO feeding study as well as cardiac health markers with dogs as they enjoy our products during long-term feeding studies.
Pets Global Inc has conducted robust internal studies and has successfully completed multiple comprehensive AAFCO feeding trials with the addition of a full complete blood count, chemistry panel, plasma amino acid profile, whole blood taurine, cardiac biomarkers as well as echocardiograms. To date, our veterinary partners evaluating the results of these studies have found all parameters to indicate our diets contribute positively to dog’s health and see no signs of concern with cardiac health while feeding our diets. You can read more about Pets Global studies here:
Zignature Kangaroo feeding Study
We would love to further the conversation with you and connect with you directly. We encourage our customers or their veterinarians to call (888) 897-7207 8 am – 4:30 pm PST. Thank you and we hope to speak with you soon.
Please feel free to read more about the latest findings on DCM by following these links:
https://www.frontiersin.org/articles/10.3389/fanim.2023.1271202/full
https://academic.oup.com/jas/article/doi/10.1093/jas/skad268/7239847
https://www.sciencedirect.com/science/article/pii/S0022316623355007
https://www.frontiersin.org/articles/10.3389/fanim.2022.846227/full
https://academic.oup.com/jas/article/98/6/skaa155/5857674
For pet parents who prefer to feed Zignature diets that do not contain legumes, Zignature Select Cuts offers the same single source protein as Zignature Original but with ancient grains.:
Links to grain-in
Links to Aafco study white papers and digestibility reports here
We will add links to BSM’s independent research studies as they are published
FAQ
What is Canine DCM?
DCM is a disease of a dog’s heart muscle and results in an enlarged heart and decreased pumping ability. As the heart and its chambers become dilated, it becomes harder for the heart to pump, and heart valves may leak, which can lead to a buildup of fluids in the chest and abdomen (congestive heart failure). DCM is prevalent in certain breeds, especially larger dogs. Most experts believe DCM is multi-factorial which means many factors such as genetics, infectious disease and sometimes nutrition can play a role.
How do I know if my dog has DCM?
Please contact your veterinarian to determine if an echocardiogram or veterinary cardiologist evaluation are deemed prudent for your dog. If your dog is showing possible signs of DCM or other heart conditions, including decreased energy, cough, difficulty breathing and episodes of collapse, you should contact your veterinarian immediately.
Is there a link between novel proteins and DCM?
There is no definitive link to any novel proteins and the development of DCM
How does Zignature formulate its food?
Our meticulously designed diets have been formulated by a thought-leading team of veterinarians, PhD animal nutritionists and veterinary research scientists to deliver the safest pet products on the market that exceed the industry’s AAFCO guide for complete and balanced nutrition for dogs.
Why are you continuing to use legumes in your diets?
Millions of dogs that suffer from severe food intolerances are able to live healthy lives because of grain-free solutions like Zignature. As no one has been able to determine if or what the association may be between a dog’s diet and this rare cardiac condition, we believe it’s important that we continue to serve the millions of dogs that thrive on our diets.
We remain confident that the pet products created by Zignature’s expert formulation team of veterinarians, PhD animal nutritionists and veterinary research scientists deliver the safest and most nutritious dietary standards available today. Our diets have always included taurine through meats and fish in all our products, which is important given that taurine is essential for optimum cardiac health.. Zignature further supplements all of its diets with extra taurine and L-Carnitine, providing some of the highest level of taurine available in the industry.
Our company was founded by pet parents who have a passion and commitment to pet health. Our meticulously designed diets have been formulated by a thought-leading team of veterinarians, PhD animal nutritionists and veterinary research scientists to deliver the safest pet products on the market that exceed the industry’s AAFCO guide for balanced and thorough nutrition.
While the vast majority of our customers thrive with our high quality, grain-free pet formula, we are taking the FDA’s recent announcement very seriously.
Any pet owners or veterinarians who have information on this matter are strongly encouraged to contact our dedicated customer care line backed by our team of veterinary experts and nutritionists. Ensuring the health of all our pet customers continues to be our top priority.
We are committed to pets being their happiest and healthiest
Zignature was created 12 years ago by pet parents with a passion and commitment to make the highest quality, most nutritious and safest pet food on the planet.
Our goal and devotion is to continue to formulate the world’s safest pet food products that are nutritionally sound and provide a path for pets to be their happiest and healthiest.
Meticulously designed diets by a team of veterinary research scientists and nutritional experts
Interest in dilated cardiomyopathy (DCM) in dogs and the ongoing FDA investigation into the long-standing pattern generated questions for us at Zignature and our valued pet parents.
Our desire is to communicate our thoughts on the ongoing FDA investigation and share with pet parents, like you, the immense confidence we have in our meticulously designed diets formulated by Zignature’s thought leading team of veterinarians, PhD animal nutritionists and veterinary research scientists. Since the founding of our company in 2010, our products are precisely formulated by this team to deliver you and your pets the safest, most nutritious pet products on the market and meet standards far above the industry’s AAFCO guide for balanced and thorough nutrition.
Taurine levels in Zignature products are some of the highest in the industry
We remain confident that the pet products created by Zignature’s expert formulation team of veterinarians, PhD animal nutritionists and veterinary research scientists deliver the safest and most nutritious dietary standards available today. Our diets have always included taurine through meats and fish in all our products, which is important given that taurine is a meaningful nutrient dogs are sometimes unable to synthesize naturally. While taurine has always been included in our diets, new studies have shown that higher taurine levels are important for dogs cardiovascular health. As a result Zignature has further supplemented all of its diets with extra taurine, providing some of the highest level of taurine available in the industry.
Currently, the FDA is not advising any dietary changes for dog eating grain-free diets.
Pets Global internal studies reveal dogs eating our diets remained in excellent cardiac health
In parallel with the FDA investigation, our own third party internal studies found that dogs eating our diets over an extended period had excellent cardiac health throughout and at the end of the study.
We have great confidence in our naturally sourced grain-free diets
As we continue to have great confidence in our naturally sourced diets that meet the needs of dogs who suffer from allergies and grain intolerances, we are providing an exclusive line designed by our expert formulation team that is nutritionally sound and grain-inclusive. We feel as a partner to pet parents, it is important for us to listen to and understand our valued extended family, and offer a variety of pet food that most align with the needs of your pet family.
As pet nutrition research progresses, we will continue to do whatever it takes to provide the highest quality, most nutritious and safest pet food on the market to keep your pet safe and healthy.
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